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    Name:
    QIU Xinghui
    Subject:
    Biochemistry and Molecular Biology
    Tel/Fax:
    +86-10-64807231  /  +86-10-64807099
    E-mail:
    qiuxh@ioz.ac.cn
    Address:
    The State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
    More:
    Group of Insect Toxicology and Biotechnology      

    Resume:

    Dr. Xing-Hui Qiu received his Master’s degree in Ecology in 1991 and Ph.D. in Zoology in 1998 from the Graduate School of Chinese Academy of Sciences. He has been appointed as Professor and the head of Insect Toxicology and Biotechnology Group of the State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology (IOZ), the Chinese Academy of Sciences.


    Research Interest:

    Dr. Qiu’s research focuses on: (1) function and regulation of cytochrome P450s, (2) molecular and evolutionary biology of insecticide resistance and (3) insect biotechnology, seeking answers to both basic questions regarding adaptation of insects to chemical stress (plant toxins and insecticides) and applied questions in pest insect control practice.


    Public Services:

    Awards and Honors:
    National Award for Natural Sciences, Third Prize, 1999
    Chinese Academy of Sciences Award for Natural Sciences. First Prize 1997
    Research Grants:
    Dr. Qiu’s research is supported by several grants from National Basic Research Program of China, National Natural Science Foundation of China.
    Selected Publication:
    1. Feng X, Yang C, Yang Y, Jun Li, Lin K, Li M, Qiu X*, 2015. Distribution and frequency of G119S mutation in ace-1 gene within Anopheles sinensis populations from Guangxi, China. Malaria Journal,14:470
    2. Liu D, Yuan Y, Li M, Qiu X*, 2015 Effects of dietary quercetin on performance and cytochrome P450 expression of the cotton bollworm, Helicoverpa armigera. Bulletin of Entomological Research, 105 (06): 771-777
    3. Sun W, Valero MC, Seong KM, Steele LD, Huang IT, Lee CH, Clark JM, Qiu X and Pittendrigh BR, 2015. A glycine insertion in the estrogen-related receptor (ERR) is associated with enhanced expression of three cytochrome P450 genes in transgenic Drosophila melanogaster. PLoS ONE, 10(3): e0118779
    4. Liu D, Zhou X, Li M, Zhu S, Qiu X*, 2014. Characterization of NADPH-cytochrome P450 reductase gene from the cotton bollworm, Helicoverpa armigera. Gene, 545: 262-270.
    5. Wan H, Liu Y, Li M, Zhu S, Li X, Pittendrigh BR, Qiu X*, 2014. Nrf2/Maf binding site-containing functional Cyp6a2 allele is associated with DDT resistance in Drosophila melanogaster. Pest Management Science, 70: 1048-1058.
    6. Zhou X, Qian K,Tong Y, Zhu JJ, Qiu X*, Zeng X*, 2014, De novo transcriptome of the hemimetabolous German cockroach (Blattella germanica). PLoS ONE, 9(9): e106932
    7. Yan Y, Zhou X, Yang J. Li M. Qiu X*, 2013. T-2 toxin is hydroxylated by chicken CYP3A37. Food and Chemical Toxicology,62: 622-627.
    8. Yang J, An J, Li M, Hou X, Qiu X*, 2013. Characterization of chicken cytochrome P450 1A4 and 1A5: Inter-paralog comparisons of substrate preference and inhibitor selectivity. Comparative Biochemistry and Physiology, Part C 157: 337–343.
    9. Yang J, Liu Z, Li M, Qiu X*, 2013. Hydroxylation of quinocetone and carbadox is mediated by CYP1As in the chicken (Gallus gallus). Comparative Biochemistry and Physiology, Part C 158:84-90.
    10. Qiu X, Sun W, McDonnell C, Li H, Steele LD, Wu J, Xie J, Muir W, Pittendrigh. BR. 2013. Genome-wide analysis of genes associated with moderate and high DDT resistance in Drosophila melanogaster. Pest Management Science, 69:930-937.
    11. Rinkevich FD, Hedtke SH, Leichter CA, Harris SA, Su C, Brady SG, Taskin V, Qiu X, Scott JG, 2012. Multiple Origins of kdr-type Resistance in the House Fly, Musca domestica. Plos One, 7(12): e52761.
    12. Gao Q, Li M, Sheng C, Scott JG, Qiu X*, 2012. Multiple cytochrome P450s overexpressed in pyrethroid resistant house flies (Musca domestica). Pesticide Biochemistry and Physiology, 104: 252-260.
    13. Qiu X*, Pan J, Li M, Li Y, 2012. PCR-RFLP methods for detection of insecticide resistance-associated mutations in the house fly (Musca domestica). Pesticide Biochemistry and Physiology, 104 : 201–205.
    14. Wang Q, Li M, Pan J, Di M, Liu Q,Meng F,Scott JG, Qiu X*, 2012. Diversity and frequencies of genetic mutations involved in insecticide resistance in field populations of the house fly (Musca domestica L.) from China. Pesticide Biochemistry and Physiology, 102:153-159.
    15. Zhou X, Li M , Sheng C, Qiu X*, 2011. NADPH-cytochrome P450 oxidoreductase from the chicken (Gallus gallus): sequence characterization, functional expression and kinetic study.  Comparative Biochemistry and Physiology, Part C, 153: 53-59.
    16. Wang D, Qiu X, Wang H, Qiao K, Wang K, 2010. Reduced fitness associated with spinosad resistance in Helicoverpa armigera. Phytoparasitica, 38:103–110.
    17. Zhou X, Sheng C, Li M, Wan H, Liu D, Qiu X*, 2010. Expression responses of nine cytochrome P450 genes to xenobiotics in the cotton bollworm Helicoverpa armigera, Pesticide Biochemistry and Physiology, 97:209-213.
    18. Zhou X, Ma C, Sheng C, Liu H, Gong P, Qiu X*, 2010. CYP9A12 and CYP9A17 in the cotton bollworm, Helicoverpa armigera: sequence similarity, expression profile and xenobiotic response. Pest Management Science, 66: 65-73.
    19. Qiu X *, Wu P, Zhang H, Li M, Yan Z, 2009. Isolation and characterization of Arthrobacter sp. HY2 capable of degrading a high concentration of p-nitrophenol. Bioresource Technology, 100: 5243-5248.
    20. Wang D, Qiu X*, Ren X, Zhang W, Wang K*,2009. Effects of spinosad on Helicoverpa armigera (Lepidoptera: Noctuidae) from China: tolerance status, synergism and enzymatic responses. Pest Management Science, 65:1040-1046.
    21. Wang D. Qiu X. Ren X, Niu F, Wang K*, 2009. Resistance selection and biochemical characterization of spinosad resistance in Helicoverpa armigera (Hubner) (Lepidoptera:Noctuidae).  Pesticide Biochemistry and Physiology, 95:90-94.
    22. Wang D, Gong P, Li M, Qiu X*, Wang K*, 2009,Sublethal effects of spinosad on survival, growth and reproduction of Helicoverpa armigera (Lepidoptera: Noctuidae). Pest Management Science, 65(2):223-227.
    23. Xu J, Yang M, Dai J, Cao H, Pan C, Qiu X*, Xu M, 2008. Degradation of acetochlor by four microbial communities.  Bioresource Technology, 99: 7797–7802.
    24. Qiu X*, Li M, Luo H, Fu T., 2007. Molecular analysis of resistance in a deltamethrin-resistant strain of Musca domestica from China. Pesticide Biochemistry and Physiology, 89(2):146-150.
    25. Zhong Q, Zhang H, Bai W, Li M, Li B, Qiu X*, 2007. Degradation of aromatic compounds and degradation pathway of 4-nitrocatechol by Ochrobactrum sp. B2. Journal of Environmental Science and Health, Part A 42: 2111-2116. 
    26. Qiu X*, Zhong Q, Li M, Bai W, Li B, 2007. Biodegradation of p-nitrophenol by methyl parathion-degrading Ochrobactrum sp. B2.  International Biodeterioration & Biodegradation, 59 (4): 297-301.
    27. Qiu X*, Bai W, Zhong Q, Li M, He F, Li B, 2006. Isolation and characterization of a bacterial strain of the genus Ochrobactrum with methyl parathion mineralizing activity. Journal of Applied Microbiology, 101: 986-994.
    28. Horne I, Qiu X, Ollis DL, Russell RJ, Oakeshott JG, 2006. Functional effects of amino acid substitutions within the large binding pocket of the phosphotriesterase OpdA from Agrobacterium sp. P230. FEMS Microbiology Letters, 259: 187-194. 
    29. Xu J, Qiu X, Dai J, Cao H, Yang M, Zhang J, Xu M.,2006, Isolation and characterization of a Pseudomonas oleovorans degrading the choloracetamide herbicide acetochlor. Biodegradation, 17: 219-225.
    30. Qiu X, Li W, Tian Y, Leng X, 2003. Cytochrome P450 monooxygenase in the cotton bollworn(Lepidoptera: Noctuidae): tissue difference and induction. Journal of Econonic Entomology, 96(4): 1283-128.