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    WANG Chenzhu
    Biochemistry and Molecular Biology
    +86-10-64807115  /  +86-10-64807099
    The State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
    Group of Insect Behavioral Physiology and Biochemistry      


    Chen-Zhu Wang received his Ph. D. degree in Beijing Agricultural University (now China Agricultural University) in 1991, mentored by Dr. Ming-Zang Zhou. In the same year he came to Institute of Zoology, the Chinese Academy of Sciences (CAS) as a postdoc with Dr. Jun-De Qin. He worked at Institute of Zoology, CAS as an associate professor from 1993 and a full professor from 1997 up to now. He had visiting research experiences with Prof. E. A. Bernays in Entomology Department in 1994 and Prof. J. G. Hildebrand in Neurobiology Department of University of Arizona in 2010, in Entomology Laboratory of Wageningen University with Dr. J. J. A. van Loon in 1998 and 2004, and in Zoology Department of University of Cambridge with Prof. M. Burrows in 2002. In 2009, he received National Science Fund for Distinguished Young Scholars from Natural Science Foundation of China.

    Research Interest:

    His research interest focuses on insect-plant interactions and chemical communications of insects. He systematically examined the coevolutionary interactions between Helicoverpa species and their host plants, including plant chemical defense to insects and insect adaptation to plant defense, and expanded the interacting insects and plants system to a multitrophic system with emphases on the impact of the third trophic level and host shift on the evolution of insect host range. He advocated and provided the evidence for that host generalization may be another right evolutionary strategy apart from host specialization, such as polyphagous insects like H. armigera. His laboratory broke through the bottleneck of interspecific hybridization between H. armigera and H. assulta for the first time, and elucidated their reproductive isolation mechanisms. In the light of coevolution, he is further studying (1) the physiological and molecular aspects of tritrophic interactions among plants, phytophagous insects and parasitoids and (2) the molecular bases of female sex pheromone signals and male olfactory responses.

    Public Services:

    Awards and Honors:

    Research Grants:

    Selected Publication:
    1. Yang K, Huang LQ, Ning C, Wang CZ. 2017. Two single-point mutations shift the ligand selectivity of a pheromone receptor between two closely related moth species. eLife 6: e29100.
    2. Li RT, Ning C, Huang LQ, Dong JF, Li X, Wang, CZ. 2017. Expressional divergences of two desaturase genes determine the opposite ratios of two sex pheromone components in Helicoverpa armigera and Helicoverpa assulta. Insect Biochemistry and Molecular Biology 90: 90-100.
    3. Di C, Ning C, Huang LQ, Wang CZ. 2017. Design of larval chemical attractants based on odorant response spectra of odorant receptors in the cotton bollworm. Insect Biochemistry and Molecular Biology 84: 48-62.
    4. Xu M, Dong JF, Wu H, Zhao XC, Huang LQ, Wang CZ. 2017. The inheritance of the pheromone sensory system in two Helicoverpa species: dominance of H. armigera and possible introgression from H. assulta. Frontiers in Cellular Neuroscience 10: 302.
    5. Xu M, Guo H, Hou C, Wu H, Huang LQ, Wang CZ. 2016. Olfactory perception and behavioral effects of sex pheromone gland components in Helicoverpa armigera and Helicoverpa assulta. Scientific Reports 6: 22998.
    6. Ning C, Yang K, Xu M, Huang LQ, Wang CZ. 2016. Functional validation of the carbon dioxide receptor in labial palps of Helicoverpa armigera moths. Insect Biochemistry and Molecular Biology 73: 12-19.
    7. Wu H, Xu M, Hou C, Huang LQ, Dong JF, Wang CZ. 2015. Specific olfactory neurons and glomeruli are associated to differences in behavioral responses to pheromone components between two Helicoverpa species. Frontiers in Behavioral Neuroscience 9.
    8. Jiang XJ, Chao N, Guo H, Jia YY, Huang LQ, Qu MJ, Wang CZ. 2015. A gustatory receptor tuned to D-fructose in antennal sensilla chaetica of Helicovera armigera. Insect Biochemistry and Molecular Biology 60:39-46.
    9. Jiang XJ, Guo H, Di C, Yu S, Zhu L, Huang LQ, Wang CZ. 2014. Sequence similarity and functional comparisons of pheromone receptor orthologs in two closely related Helicoverpa species. Insect Biochemistry and Molecular Biology 48:63-74.
    10. Guo H, Huang LQ, Pelosi P, Wang CZ. 2012. Three pheromone-binding proteins help segregation between two Helicoverpa species utilizing the same pheromone components. Insect Biochemistry and Molecular Biology42: 708-716.