Location: Home > Scientists
  Principal Investigators
Regenerative Medicine
+86-10-64807315  / 
State Key Laboratory of Membrane Biology , Institute of Zoology, Chinese Academy of Siences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
Group for Bioinspired Engineering      
Dr. Gu has an interdisciplinary training in materials chemistry and stem cells. During his first doctoral career (2009-2013), Dr. Gu has investigated the pluripotent state of humans, primates and other animal species towards identifying definitive ways for regulating, characterising and purifying human pluripotent stem cells. Drawing from his studies in Beijing, he completed a second PhD (2013-2017) at University of Wollongong where he has developed novel biomaterials and used bioprinting for advanced human stem cell culture, differentiation and 3D tissue engineering, which is overcoming the limitations of conventional 2D culture methods, enabling better control of stem cell survival, fate and tissue organisation for more effective cell and tissue modeling in vitro. Gu laboratory focuses on the developing novel biomaterials and advanced technologies including 3D/4D bioprinting to regulate stem cell fate and to fabricate functional 3D organs and even live organisms in vitro and applying them to understanding the mechanism of life and establish novel therapeutic methods

Research Interests:
Developing novel biomaterials and 3D/4D bioprinting technologies and in vitro organ fabrication.

Awards and Honors:

2017 Outstanding Thesis at UOW
2017 Chinese Government Award for Outstanding Self-Financed Students Abroad

Professional Activities:

Research Grants:
2017-2022, Subproject of the Strategic Priority Research Program of the Chinese Academy of Sciences, PI
2020-2022, e Scientific Instrument Developing Project of the Chinese Academy of Sciences, PI

Selected Publications:
  1. Zhao, H., Xu, J., Peng, K., Fu, X., Zhang, E., Lv, F., Liu, L., Zhang, N., Wang, Y., Wang, S., Gu, Q. (2020). Supramolecular Nanofibers for Encapsulation and In Situ Differentiation of Neural Stem Cells. Adv Healthc Mater, e1901295.
  2. Gu, Z., Guo, J., Wang, H., Wen, Y., and Gu, Q. (2020) Bioengineered microenvironment to culture early embryos. Cell Proliferation 53, e12754.
  3. Sun, H., Liu, J., Li, S., Zhou, L., Wang, J., Liu, L., Lv, F., Gu, Q#., Wang, S#. (2019). Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid β Assembly. Angewandte Chemie International Edition 58, 5988-5993.
  4. Gu, Z., Gao, Z., Liu, W., Wen, Y., and Gu, Q. (2019). A Facile Method to Fabricate Anisotropic Extracellular Matrix with 3D Printing Topological Microfibers. Materials 12, 3944.
  5. Wang, L*., Wu, W*., Gu, Q*., Liu, Z., Li, Q., Li, Z., Fang, J., Liu, W., Wu, J., and Zhang, Y. (2019a). The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies. Protein & cell, 1-6.
  6. Sun, H., Lv, F.T., Liu, L.B., Gu, Q.#, Wang, S#. (2018) Conjugated polymer materials for photothermal therapy. Advanced Theraputics 1, 1800057.
  7. Gu, Q., Tomaskovic-Crook, E., Wallace, G.G., and Crook, J.M. (2018) Engineering Human Neural Tissue by 3D Bioprinting, in Biomaterials for Tissue Engineering. Methods in Molecular Biology. 1758: 129-138.
  8. Gu, Q., Tomaskovic-Crook, E., Wallace, G.G., and Crook, J.M. (2017).3D Bioprinting Human Induced Pluripotent Stem Cell Constructs For In Situ Cell Proliferation and Successive Multi-Lineage Differentiation. Advanced Healthcare Materials, doi: 10.1002/adhm.201700175. (cover).
  9. Gu, Q., Tomaskovic-Crook, E., Lozano, R., Chen, Y., Kapsa, R.M., Zhou, Q., Wallace, G.G., and Crook, J.M. (2016). Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells. Advanced Healthcare Materials 5, 1429-1438. (frontispiece)
  10. Chen, Y*., Gu, Q*., Yue, ZL., Crook, Jeremy., Moulton, Simon., Cook, Mark., and Wallace, Gordon. (2017). Development of drug-loaded polymer microcapsules for treatment of epilepsy. Biomaterials Science, 5(10), 2159-2168.
  11. Javadi, M., Gu, Q., Naficy, S., Farajikhah, S., Crook, J., Wallace, G., Moulton, S. (2017) Conductive Tough Hydrogel for Bio-applications. Macromolecular Bioscience. (online)
  12. Zhang, H.R., Gu, Q., Wallace, G.G., Higgins, M.J. (2018). Effect of Electrochemical Oxidation and Reduction on Cell De-Adhesion at the Conducting Polymer-Live Cell Interface as revealed by Single Cell Force Spectroscopy. Biointerphases. 13(4), p.041004.
  13. Gu, Q*., Zhu, H*., Li, J., Li, X., Hao, J., Wallace, G.G., & Zhou, Q. (2016). Three Dimensional Bioprinting Speeds Up Smart Regenerative Medicine. National Science Review 3 (3), 331-344.
  14. Gu, Q*., Hao, J*., Lu, Y., Wang, L., Wallace, G. G., & Zhou, Q. (2015). Three-Dimensional Bio-printing. Science China Life Sciences 58, 411-419. (cover)