Location: Home > Scientists
  Principal Investigators
Name:
 Qi Gu
Subject:
 Regenerative Medicine
Tel/Fax:
 +86-10-64807315  / 
E-mail:
 qguATioz.ac.cn
Address:
 1 Beichen West Road, Chaoyang District, Beijing
More:
 Group for Bioinspired Engineering      
Resume:

Dr Gu is currently appointed as a Full Professor, Director of Chinese Academy of Sciences (CAS) Engineering Lab for Intelligent Organ Manufacturing and group leader of Bioinspired Engineering, at Institute for Stem Cell and Regeneration (ISCR) | Institute of Zoology (IOZ), CAS. The primary focus of Gu’s laboratory is to develop novel biomaterials and advanced technologies including 3D/4D bioprinting to regulate cell fate spatiotemporally, fabricate 3D organs functionally, and create meaningful therapeutic methods based on the mechanism of developmental biology and in turn deepen the understanding of what is life. Dr. Gu has made significant contributions to the field of 3D bioprinting, specifically for human stem cell involved tissue engineering. He has recently achieved notable progress in the 3D printing of complex vascular networks and skeletal muscle and in directing cell movement in a spatially controlled manner. Dr. Gu has published over 30 peer-reviewed journal articles as a first-author or corresponding author in prestigious journals including  including Adv. Mater., Adv. Funct. Mater., Angew. Chem. Int. Ed., Mater. Horiz., Adv. Healthc. Mater., and ACS Appl. Mater. Interfaces. Additionally, he has been invited to write 3 book chapters and is a co-inventor on seven patents.

Research Interests:
Developing novel biomaterials and 3D/4D bioprinting technologies and in vitro organ fabrication.

Awards and Honors:
  • 2022 Excellent Young Scientists Fund, National Natural Science Foundation of China (Department of Interdisciplinary Sciences, NSFC)
  • 2022 Chinese Society of Stem Cell Research (CSSCR) Young Investigator Award
  • 2017 Chinese Government Award for Outstanding Self-Financed Students Abroad
  • 2017 Outstanding Thesis at UOW

Professional Activities:

Bioactive Materials, Early Career Editorial Board

Cell Proliferation, Editorial Board

International Journal of Bioprinting, Guest Editor

Research Grants:
  • 2021-2024, The Regional Innovation Development Joint Fund of the National Natural Science Foundation
  • 2017-2022, Subproject of the Strategic Priority Research Program of the Chinese Academy of Sciences, PI
  • 2020-2022, e Scientific Instrument Developing Project of the Chinese Academy of Sciences, PI

Selected Publications:
  1. Gu, Z.*, Guo, J.*, Zhai, J.*, Feng, G.*, Wang, X., Gao, Z., Li, K., Ji, S., Wang, L., Xu, Y., Chen, X., Wang, Y., Guo, S., Yang, M., Li, L., Han, H., Jiang, L., Wen, Y., Wang, L., Hao, J., Li, W., Wang, S.T.#, Wang, H.M.#, and Gu, Q.# (2022) A Uterus-inspired Niche Drives Blastocyst Development to the Early Organogenesis. Adv. Sci. (frontispiece)
  2. Liu, X.*, Wang, X.*, Zhang, L.*, Sun, L.*, Wang, H., Zhao, H., Zhang, Z., Liu, W., Huang, Y., Ji, S., Zhang, J., Li, K., Song, B., Li, C., Zhang, H., Li, S., Wang, S.#, Zheng, X.#, Gu, Q.#(2021) 3D Liver Tissue Model with Branched Vascular Networks by Multimaterial Bioprinting. Adv. Healthc. Mater., 2101405. (Cover)
  3. Fan, T., Wang, S., Jiang, Z., Ji, S., Cao, W., Liu, W., Ji, Y., Li, Y., Shyh-Chang, N. #, Gu, Q. #, (2021). Controllable assembly of skeletal muscle-like bundles through 3D bioprinting. Biofabrication, 14(1), p.015009.
  4. Gu, Q., Tomaskovic-Crook, E., Lozano, R., Chen, Y., Kapsa, R.M., Zhou, Q., Wallace, G.G.#, and Crook, J.M.# (2016). Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells. Adv. Healthc. Mater. 5, 1429-1438. (frontispiece)
  5. Gu, Q., Tomaskovic-Crook, E., Wallace, G.G.#, and Crook, J.M.# (2017).3D Bioprinting Human Induced Pluripotent Stem Cell Constructs For In Situ Cell Proliferation and Successive Multi-Lineage Differentiation. Adv. Healthc. Mater., 6(17), p.1700175. (Cover).
  6. Ding, S.L., Liu, X., Zhao, X.Y., Wang, K.T., Xiong, W., Gao, Z.L., Sun, C.Y., Jia, M.X., Li, C., Gu, Q.#, Zhang, M.Z.#, (2022). Microcarriers in application for cartilage tissue engineering: Recent progress and challenges. Bioact. Mater.
  7. Zhao, H., Huang, Y., Lv, F., Liu, L., Gu, Q.#, Wang, S.# (2021) Biomimetic 4D-Printed Breathing Hydrogel Actuators by Nanothylakoid and Thermoresponsive Polymer Networks. Adv. Funct. Mater., 2105544.
  8. Zhao, H., Xu, J., Yuan, H., Zhang, E., Dai, N., Gao, Z., Huang, Y., Lv, F., Liu, L., Gu, Q.# and Wang, S.#, (2021). 3D printing of artificial skin patches with bioactive and optically active polymer materials for anti-infection and augmenting wound repair. Mater. Horiz.
  9. Zhao, H.*, Xu, J.*, Zhang, E., Qi, R., Huang, Y., Lv, F., Liu, L., Gu, Q.#, Wang, S.# (2021). 3D Bioprinting of Polythiophene Materials for Promoting Stem Cell Proliferation in Nutritionally Deficient Environment. ACS Appl. Mater. Interfaces 13(22): 25759-25770.
  10. Peng, K., Liu, X., Zhao, H., Lu, H., Lv, F., Liu, L., Huang, Y., Wang, S.# and Gu, Q.# (2021). 3D Bioprinting of Reinforced Vessels by Dual-Cross-linked Biocompatible Hydrogels. ACS Appl. Bio Mater. 4(5), 4549–4556.
  11. Salahuddin, B., Wang, S., Sangian, D., Aziz, S.#, Gu, Q.# (2021). Hybrid Gelatin Hydrogels in Nanomedicine Applications. ACS Appl. Bio Mater. 4(4), 2886–2906.
  12. Li, X.*, Wang, Y.*, Ma, R.*, Liu, X., Song, B., Duan, Y., Guo, J., Feng, G., Cui, T., Wang, L., Hao, J.#, Wang, H.M.#, Gu, Q.# (2021). Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro. Biomed. Mater. 16 (3), 035023.
  13. Zhao, H., Xu, J., Peng, K., Fu, X., Zhang, E., Lv, F., Liu, L., Zhang, N., Wang, Y., Wang, S.#, Gu, Q.# (2020). Supramolecular Nanofibers for Encapsulation and In Situ Differentiation of Neural Stem Cells. Adv Healthc Mater, 9 (1), 1901295.
  14. Gu, Z., Guo, J., Wang, H., Wen, Y., and Gu, Q. (2020) Bioengineered microenvironment to culture early embryos. Cell Prolif 53, e12754.
  15. Sun, H., Liu, J., Li, S., Zhou, L., Wang, J., Liu, L., Lv, F., Gu, Q#., Wang, S#. (2019). Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid β Assembly. Angew. Chem. Int. Ed 58, 5988-5993.
  16. Gu, Z., Gao, Z., Liu, W., Wen, Y., and Gu, Q. (2019). A Facile Method to Fabricate Anisotropic Extracellular Matrix with 3D Printing Topological Microfibers. Materials 12, 3944.
  17. Gu, Q., Tomaskovic-Crook, E., Wallace, G.G., and Crook, J.M. (2018) Engineering Human Neural Tissue by 3D Bioprinting, in Biomaterials for Tissue Engineering. Methods Mol. Biol. 1758: 129-138.
  18. Gu, Q.*, Hao, J.*, Lu, Y., Wang, L., Wallace, G. G., & Zhou, Q. (2015). Three-Dimensional Bio-printing. Sci. China Life Sci. 58, 411-419. (cover)
  19. Gu, Q.*, Zhu, H. , Li, J., Li, X., Hao, J., Wallace, G.G., & Zhou, Q. (2016). Three Dimensional Bioprinting Speeds Up Smart Regenerative Medicine. Natl. Sci. 3 (3), 331-344.