1.教育经历：

　　2008-2012年 河北农业大学 生物技术 学士学位

　　2012-2017年 北京大学 细胞生物学 博士学位

　　2.工作经历：

　　2017年7月-2020年8月 中国科学院生物物理研究所，副研究员

　　2020年9月至今 中国科学院动物研究所，副研究员

　　综合运用多组学手段多层次解析衰老及相关疾病的发生发展机制，探究新型干预靶标。

（#共同第一作者）

1. S. Wang^#, Y. Zheng^#, J. Li^#, Y Yang^#, W. Zhang^#, M. Song, Z. Liu, Z. Min, H. Hu, Y. Jing, X. He, L. Sun, L. Ma, C. R. Esteban, P. Chan, J. Qiao, Q. Zhou, J. C. I. Belmonte, J. Qu, F. Tang, and G.-H. Liu, “Single-cell transcriptomic atlas of primate ovarian aging,” Cell, vol. 180, no. 3, pp. 585-600, 2020. (Cover story)
2. W. Zhang^#, J. Li^#, K. Suzuki^#, J. Qu^#, P. Wang, J. Zhou, X. Liu, R. Ren, X. Xu, A. Ocampo, T. Yuan, J. Yang, Y. Li, L. Shi, D. Guan, H. Pan, S. Duan, Z. Ding, M. Li, F. Yi, R. Bai, Y. Wang, C. Chen, F. Yang, X. Li, Z. Wang, E. Aizawa, A. Goebl, R. D. Soligalla, P. Reddy, C. R. Esteban, F. Tang, G.-H. Liu, and J. C. I. Belmonte, “A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging,” Science, vol. 348, no. 6239, pp. 1160–1163, 2015.
3. J. Li^#, Y. Zheng^#, P. Yan^#, M. Song^#, S. Wang^#, L. Sun, Z. Liu, S. Ma, P. Chan, Q. Zhou, J. C. I. Belmonte, W. Zhang, G.-H. Liu, F. Tang, J. Qu, “A Single-cell Transcriptomic Atlas of Primate Pancreatic Islet Aging,” National Science Review, vol. 8, no. 2, 2021. DOI: 10.1093/nsr/nwaa127.
4. J. Li^#, X. Zhou^#, X. Liu^#, J. Ren^#, J. Wang, W. Wang, Y. Zheng, X. Shi, T. Sun, Z. Li, A. Kang, F. Tang, L. Wen, and W. Fu, “Detection of Colorectal Cancer in Circulating Cell-Free DNA by Methylated CpG Tandem Amplification and Sequencing,” Clinical Chemistry, vol. 65, no. 7, pp. 916-926, 2019.
5. J. Yang^#, J. Li^#, K. Suzuki^#, X. Liu, J. Wu, W. Zhang, R. Ren, W. Zhang, P. Chan, J. C. I. Belmonte, J. Qu, F. Tang, and G.-H. Liu, “Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding,” Cell Research, vol. 27, no. 9, pp. 1178–1181, 2017.
6. L. Wen^#, J. Li^#, H. Guo^#, X. Liu^#, S. Zheng, D. Zhang, W. Zhu, J. Qu, L. Guo, D. Du, X. Jin, Y. Zhang, Y. Gao, J. Shen, H. Ge, F. Tang, Y. Huang, and J. Peng, “Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients,” Cell Research, vol. 25, no. 11, pp. 1250–1264, 2015.
7. W.Wang, Y. Zheng, S. Sun, W. Li, M. Song, Q. Ji, Z. Wu, Z. Liu, Y. Fan, F. Liu, J. Li, C. R. Esteban, Si Wang, Qi Zhou, J. C. I. Belmonte, W. Zhang, J. Qu, F. Tang, G.-H. Liu, “A genome-wide crispr-based screen identifies kat7 as a driver of cellular senescence,” Science Translational Medicine, vol. 13, pp. 2655, 2021.
8. L. Deng, R. Ren, Z. Liu, M. Song, J. Li, Z. Wu, X. Ren, L. Fu, W. Li, W. Zhang, P. Guillen, J. C. I. Belmonte, P. Chan, J. Qu & G.-H. Liu, “Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis,” Nature Communications, vol. 10, no. 1, pp. 3329, 2019.
9. X. Liu, J. Ren, N. Luo, H. Guo, Y. Zheng, J. Li, F. Tang, L. Wen, J. Peng, “Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq),” Clinical Epigenetics, vol. 11, no. 1, pp. 93, 2019.
10. P. Wang, Z. Liu, X. Zhang, J. Li, L. Sun, Z. Ju, J. Li, P. Chan, G.-H. Liu, W. Zhang, M. Song, and J. Qu, “CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeostasis of human vascular cells,” Protein & Cell, vol. 9, no. 11, pp. 945-965, 2018.
11. H. Pan, D. Guan, X. Liu, J. Li, L. Wang, J. Wu, and J. Zhou, “SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2,” Cell Research, vol. 26, no. 2, pp. 190–205, 2016.
12. S. Duan, G. Yuan, X. Liu, R. Ren, J. Li, W. Zhang, J. Wu, X. Xu, L. Fu, Y. Li, J. Yang, W. Zhang, R. Bai, F. Yi, K. Suzuki, H. Gao, C. R. Esteban, C. Zhang, J. C. Izpisua Belmonte, Z. Chen, X. Wang, T. Jiang, J. Qu, F. Tang, and G.-H. Liu, “PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype.,” Nature Communications, vol. 6, pp. 10068, 2015.