研究队伍
院士专家
青年千人
百人计划
杰出青年
研究员
副研究员
人才招聘
现在位置::首页 > 研究队伍

姓  名:
王宪辉
学  科:
电话/传真:
+86-10-64807220 / +86-10-64807099
电子邮件:
wangxh@ioz.ac.cn
通讯地址:
北京市朝阳区北辰西路1号院5号
中国科学院动物研究所 农业虫害鼠害综合治理研究国家重点实验室 100101
更多信息:
行为遗传学研究组     
简历:
  王宪辉,中国科学院动物研究所研究员,行为遗传学研究组组长。2004年中国科学院动物研究所获博士学位,然后留所工作,2005-2007年在美国马里兰大学从事博士后研究。研究工作以我国重要的农业害虫——飞蝗为模式系统,采用基因组学和其它多学科交叉的手段,来研究害虫种群爆发和迁飞的关键科学问题。目前工作主要集中于飞蝗两型转变的分子调控机制方面。迄今已在Nature commnications, Annual Review of Entomology, PNAS, PloS GeneticsRNA Biology,Insect Molecular Biology, Journal of Insect Physiology等国内外学术期刊发表论文20多篇。主持国家自然科学基金、973等多项国家级课题。现担任中国昆虫学会昆虫基因组学专业委员会副主任委员,中国动物学会动物行为学专业委员会理事,北京昆虫学会理事,昆虫学报、应用昆虫学报期刊编委等学术职务。
研究领域:
  主要以我国重要的农业大害虫——飞蝗为研究对象,以其生态适应性为科学问题,开展了三个方面的工作:(1)飞蝗低温适应性机制的研究;(2)飞蝗两型转变分子机制的研究;(3)飞蝗表观遗传学机制的研究。通过这些工作,来探索和揭示基因的表达调控在生物体适应环境中的作用。 
社会任职:
获奖及荣誉:
承担科研项目情况:
  1. 中科院战略性先导科技专项、XDB11010100、信息流外周神经感知机制2014/07-2019/06、主持。
  2. 国家自然科学基金面上项目,31472047、乙酰肉碱参与飞蝗两型转变调控的表观遗传机制研究、2015/01-2018/12、主持。
  3. 国家重点发展基础研究计划(973计划)课题,2012CB114100-2、害虫暴发成灾的行为遗传机理、2012/01-2016/12、在研、子课题主持。
  4. 国家自然科学基金面上项目,30970407、Hexamerin基因家族在飞蝗型变过程中的功能分析、2010/01-2012/12、已结题、主持。
  5. 农业部转基因专项重点课题,2009ZX08009-099B、昆虫抗冻蛋白基因的克隆和功能鉴定、2009/01-2012/12、结题、主持。
  6. 中科院创新课题,2010-Biols-CAS-0304、非编码RNA的鉴定和算法开发、2010/01-2012/12、结题、主持。
  7. 国家自然科学基金重点项目,30830022、飞蝗两型转变的基因组学研究、2008/01-2012/12、已结题、参加。
  8. 北京市科委项目,动物与人科普平台建设、2007/01-2008/12、已结题、主持。
  9. 国家自然科学基金面上项目,30330110、利用OligoDNA微阵列技术研究飞蝗低温适应性的分子机理、2006/01-2008/12、已结题、主持。
  10. 国家重点发展基础研究计划(973计划),2006CB102000-1、害虫生长发育与生殖调控的分子机制、2006/01-2011/12、已结题、子课题主持。
  11. 国家科技部863计划课题、2003AA222080、飞蝗散居、群居两型转变分子机理的规模化研究、2004/01-2005/12、已结题、参加。
  12. 国家自然科学基金重点项目,30330110、飞蝗对低温胁迫的适应性机理研究、2003/01-2007/12、已结题、参加。
代表论著:
  1. Hou, L., Yang, P.C., Jiang, F., Liu, Q., Wang, X.H. *, Kang, L. *  2017. The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition. eLife 10.7554/eLife.22526. (*Co-corresponding author)
  2. Wei, J.N., Shao, W.B., Wang, X.H., Ge, J., Chen, X.Y., Yu, D., Kang L.* 2017. Composition and emission dynamics of migratory locust volatiles in response to changes in developmental stages and population density.Insect Science 24: 60-72.
  3. Li, Y., Zhang, J., Chen, D.F., Yang, P.C., Jiang, F., Wang, X.H.*, Kang, L.* 2016. CRISPR/Cas9 in locusts: Successful establishment of an olfactory deficiency line by targeting the mutagenesis of an odorant receptor co-receptor (Orco). Insect Biochemistry and Molecular Biology 79: 27-31. (*Co-corresponding author)
  4. Chen, B., Wang, X.H., Tu, Z.J., Huang, Y.P. 2016. Leap forward with insect genomics preface. Insect Science 23: 332-334.
  5. Li, J., Lu, Z.K., He, J., Chen, Q.Q., Wang, X.H., Kang, L., Li, X.D.* 2016. Alternative exon‐encoding regions of Locusta migratoria muscle myosin modulate the pH dependence of ATPase activity. Insect Molecular Biology doi: 10.1111/imb.12254
  6. Guo, S.Y., Jiang, F., Yang, P.C., Liu, Q., Wang X.H. *, Kang, L. * 2016. Characteristics and expression patterns of histone-modifying enzyme systems in the migratory locust. Insect Biochemistry and Molecular Biology 76: 18-28.  (*Co-corresponding author)
  7. Xu, J. J., Wan, G.J., Hu, D.B., He, J., Chen, F.J., Wang, X.H., Hua, H.X., Pan, W.D.* 2016. Molecular characterization, tissue and developmental expression profiles of cryptochrome genes in wing dimorphic brown planthoppers, Nilaparvata lugens. Insect science doi: 10.1111/1744-7917.12256.
  8. Wang, Z.F., Yang, P.C., Chen D.F., Jiang, F., Li, Y., Wang, X.H. *, Kang, L. *, 2015 Identification and functional analysis of olfactory receptor family reveal unusual characteristics of the olfactory system in the migratory locust. Cellular and Molecular Life Sciences, 72, 4429-4443. (*Co-corresponding author)
  9. Hou, L., Jiang, F., Yang, P.C., Wang, X.H.*, Kang, L.*, 2015 Molecular characterization and expression profiles of neuropeptide precursors in the migratory locust. Insect Biochemistry and Molecular Biology, 63, 63-71. (*Co-corresponding author)
  10. Wang, X.H., Fang, X.D., Yang, P.C., Jiang, X.T., Jiang, F., Zhao, D.J., Li, B.L., Cui, F., Wei, J.N., Ma, C., Wang, Y.D., He, J., Luo, Y., Wang, Z.F., Guo, X.J., Guo, W., Wang, X.S., Zhang, Y., Yang, M.L., Hao, S.G., Chen, B., Ma, Z.Y., Yu, D., Xiong, Z.Q., Zhu, Y.B., Fan, D.D., Han, L.J., Wang, B., Chen, Y.X., Wang, J.W., Yang, L., Zhao, W., Feng, Y., Chen, G.X., Lian, J.M., Li, Q.Y., Huang, Z.Y., Yao, X.M., Lv, N., Zhang, G.J., Li, Y.R., Wang, J., Wang, J., Zhu, B.L., Kang, L.*, 2014 Locust genome sequence provides insight into swarm formation and long-distance flight. Nature Communications 10.1038/ncomms3957.
  11. Wang, X.H., Kang, L., 2014. Molecular mechanisms of phase change in locusts. Annual Review of Entomology, 59, 225-243.
  12. Luo, Y., Wang, X.H.*, Yu, D., Chen, B., Kang, L., 2013. Differential responses of migratory locusts to systemic RNA interference via double-stranded RNA injection and feeding. Insect Molecular Biology, 22:574-583. (*The first co-author)
  13. Jiang, F., Yang, M.L., Guo, W., Wang, X.H., Kang, L., 2012, Large-scale transcriptome analysis of retroelements in the migratory locust, Locusta migratoria. PLoS One, 7: e40532.
  14. Wu, R., Wu, Z.M., Wang, X.H.*, Yang, P.C., Yu, D., Zhao, C.X., Xu, G.W. and Kang L., 2012. Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts. Proceedings of the National Academy of Sciences of (USA), 109: 3259-3263. (*The first co-author)
  15. Luo, Y., Wang, X.H.*, Yu, D., Kang, L., 2012. The SID-1 double-stranded RNA transporter is not required for systemic RNAi in the migratory locust. RNA Biology, 9:1-6. (*The first co-author)
  16. Wang, H.S., Ma, Z.Y., Cui, F. Wang, X.H., Guo, W., Yang, P.C. and Kang L., 2012. Parental phase status affects the cold hardiness of progeny eggs in locusts. Functional Ecology, 26:379–389.
  17. Guo, W., Wang, X.H.*, Ma, Z.Y., Xue, L., Han, J.Y., Yu, D., and Kang L., 2011. CSP and takeout genes modulate the switch between attraction and repulsion during behavioral phase change in the migratory locust. PLoS Genetics, 7: e1001291, 1-13. (*The first co-author)
  18. Ma, Z.Y., Guo, W., Guo, X.J., Wang, X.H., Kang L., 2011, Modulation of behavioral phase changes of the migratory locust by the catecholamine metabolic pathway. Proceedings of National Academy of Sciences (USA), 108: 3882-3887.
  19. Zhang, Y., Wang, X.H., and Kang L., 2011. A k-mer scheme to predict piRNAs and characterize locust piRNAs. Bioinformatics, 27: 771–776.
  20. Guo, W., Wang, X.H.*, Zhao, D.J., Yang, P.C. and Kang L., 2010. Molecular cloning and temporal-spatial expression of I element in gregarious and solitary locusts. Journal of Insect Physiology, 56: 943-948. (*The first co-author)
  21. Wang, X.H., Qi, X.L., and Kang L., 2010. Geographic differences on accumulation of sugars and polyols in locust eggs in response to cold acclimation. Journal of Insect Physiology, 56: 966-970.
  22. Baker, R.H., Morgan, J., Wang, X.H., Boore, J.L. and Wilkinson, G.S., 2009. Genomic analysis of a sexually-selected character: EST sequencing and microarray analysis of eye-antennal imaginal discs in the stalk-eyed fly Teleopsis dalmanni (Diopsidae). BMC Genomics, 10: 361.
  23. Wang, H.S., Wang, X.H.*, Guo, W., Zhang, S.F. and Kang L., 2007. cDNA cloning of heat shock proteins and their expression in the two phases of the migratory locust. Insect Molecular Biology, 16: 207-219. (*The first co-author)
  24. Qi, X.L., Wang, X.H*. and Kang L., 2007. Influence of soil moisture on egg cold hardiness in the migratory locust Locusta migratoria (Orthoptera:Acridiidae). Physiol. Entomol., 32: 219-224. (*The first co-author)
  25. Jing, X.H., Wang, X.H. and Kang L., 2005. Chill injury in the eggs of the migratory locust, Locusta migratoria (Orthoptera: Acrididae): the time-temperature relationship with high-temperature interruption. Insect Science, 12: 171-178.
  26. Wang, X.H., Kang L., 2005. Differences in egg thermotolerance between tropical and temperate populations of the migratory locust Locusta migratoria (Orthoptera: Acridiidae). Journal of Insect Physiology, 51: 1277-1285.
  27. Wang, X. H. and Kang L., 2003. Rapid cold hardening in young hoppers of the migratory locust Locusta migratoria L. (Orthoptera:Acridiidae). CryoLetters,24: 331-340.
  28. Wang, X.H., QI X.L., Kang L. 2003. Rapid cold hardening process of insects and its ecological adaptive significance.Prog. Nat. Sci. 13: 641-647.
  29. 崔宁宁,宋希明,邹元平,郝树广,许永玉, 王宪辉* 2013 应用差示扫描量热法检测昆虫总蛋白的热滞活性,昆虫学报,56:131-135. (*通讯作者
  30. 于芹,安国利,王宪辉*, 2011. 昆虫Takeout蛋白家族的研究进展。应用昆虫学报,48: 404-409.(*通讯作者
  31. 冯云甲,徐洪富,王宪辉*,2012 黄粉虫不同抗冻蛋白基因家族成员的低温应激表达,应用昆虫学报,49:681-685. (*通讯作者
  32. 王宪辉, 陈兵, 康乐, 2003. 飞蝗热休克蛋白70cDNA片段的克隆和序列分析. 动物学研究,24:256-259.
  33. 魏佳宁,王宪辉,孙玉诚,鲁敏,张永军,王桂荣,徐卫华,康乐.2012 害虫的遗传与行为调控,应用昆虫学报,2:299-308.
  34.  王宪辉, 徐洪富, 许永玉, 刘勇, 周真, 2003. 甜菜夜蛾雌性生殖系统结构、发育分级及在测报上的应用. 植物保护学报, 30:261-266.
  35. 王宪辉, 徐洪富, 许永玉, 2001. 昆虫分子生物学的一些研究进展. 山东农业大学学报(自然版), 1:95-98.
写给考生的话: