研究队伍
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青年千人
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姓  名:
邹 振
学  科:
基因组学
电话/传真:
+86-10-64807191 / +86-10-64807099
电子邮件:
zouzhen@ioz.ac.cn
通讯地址:
北京市朝阳区北辰西路1号院5号
中国科学院动物研究所 农业虫害鼠害综合治理研究国家重点实验室 100101
更多信息:
昆虫免疫和发育研究组     
简历:

  邹振,男,博士,研究员,博士生导师;中国科学院动物研究所昆虫免疫和发育研究组课题组组长。
  1997年于华东理工大学获得生物化学工程学士学位,2005年于美国俄克拉荷马州立大学获得昆虫学博士学位。其后分别在俄克拉荷马州立大学和加州大学河滨分校进行博士后研究,于2010.10起担任助理研究员。2012年7月,任中国科学院动物研究所昆虫免疫和发育学研究组组长,研究员,博士生导师,并入选青年千人计划、百人计划。现任中国昆虫学会常务理事、中国昆虫学会国际交流合作工作委员会主任、昆虫发育与遗传专业委员会、昆虫生理生化与分子生物学专业委员会委员、中华预防医学会媒介生物学及控制分会委员、北京市昆虫学会常务理事、昆虫学报编委、中国媒介生物学及控制杂志编委。
  主要从事分子生物学和媒介生物学的研究,聚焦于昆虫天然免疫和发育,首先以鳞翅目害虫和吸血昆虫这两类昆虫为研究对象,利用寄生蜂、真菌等外缘生物控制因子,整合生理、生化、细胞、分子、遗传和组学研究方法和手段,在细胞、器官和个体水平上,对昆虫免疫、生殖发育等方面进行研究。发表SCI论文四十多篇,以主要作者发表于Immunity, PNAS, EMBO Report, Nature Commun, PLoS Genetics, PLoS Pathogens等SCI期刊上。为DCI, IBMB, BMC Genomics, PLoS One等20种杂志审稿人。

研究领域:
  目前有三个相辅相成的研究重点:非脊椎动物免疫系统的比较进化:卫生和农业昆虫的抗真菌、抗病毒免疫反应,激素调控的昆虫生殖生物学。
社会任职:
获奖及荣誉:
  2005年度国家优秀留学生奖学金、2005年度美国昆虫学会的Student Recognition Award in Insect Physiology, Biochemistry, Toxicology, and Molecular Biology、2017。
承担科研项目情况:
代表论著:
  1. Yuan C, Xing L, Wang M, Wang X, Yin M, Wang Q, Hu Z#, and Zou Z# (2017). Inhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera. PLoS Pathog13, e1006645.
  2. Wang X, Hou Y, Saha TT, Pei G, Raikhel AS#, Zou Z#. Hormone and receptor interplay in the regulation of mosquito lipid metabolism. Proc Natl Acad Sci U S A. 2017; 114(13):E2709-E2718. doi: 10.1073/pnas.1619326114.
  3. Wang Y, Jiang H, Cheng Y, An C, Chu Y, Raikhel AS, Zou Z#. Activation of Aedes aegypti prophenoloxidase-3 and its role in the immune response against entomopathogenic fungi. Insect Mol Biol. 2017 May 27. doi: 10.1111/imb.12318.
  4. Xing L, Yuan C, Wang M, Lin Z, Shen B, Hu Z, Zou Z#. Dynamics of the interaction between cotton bollworm Helicoverpa armigera and nucleopolyhedrovirus as revealed by integrated transcriptomic and proteomic analyses. Mol Cell Proteomics.2017; pii: mcp.M116.062547. doi: 10.1074/mcp.M116.062547.
  5. Zhao LL, Zhang X, Wei Y, Zhou J, Zhang W, Qin P, Chinta S, Kong X, Liu Y, Yu H, Hu S, Zou Z#, Butcher RA#, Sun JH#. Ascarosides coordinate the dispersal of a plant-parasitic nematode with the metamorphosis of its vector beetle. Nat Commun. 2016; 7:12341, doi: 10.1038/ncomms. 12341.
  6. Zhao B, Hou Y, Wang J, Kokoza VA, Saha TT, Wang XL, Lin L, Zou Z#, Raikhel AS#. Determination of juvenile hormone titers by means of LC-MS/MS/MS and a juvenile hormone-responsiveGal4/UAS system in Aedes aegypti mosquitoes. Insect Biochem Mol Biol. 2016; 77:69-77, doi: 10.1016/j.ibmb. 2016.08.003.
  7. Roy, S., Saha, T. T., Johnson, L., Zhao, B., Ha, J., White, K. P., Girke, T., Zou, Z#. and Raikhel, A. S#. Regulation of gene expression patterns in mosquito reproduction. PLoS Genet. 2015; 11(8), e1005450. doi: 10.1371/journal.pgen. 1005450. 
  8. Hou, Y., Wang X.L., Saha, T.T., Roy, S., Zhao, B., Raikhel, A.S.#, Zou Z#. Temporal Coordination of Carbohydrate Metabolism during Mosquito Reproduction. PLoS Genet. 2015; 11(7): e1005309. doi: 10.1371/journal.pgen. 1005309.
  9. Meng, Q., Yu, H.Y.,  Zhang, H., Zhu, W., Wang, M.L., Zhang, J.H., Zhou, G.L., Li, X., Qin, Q.L.#, Hu, S.N.#, Zou, Z#.  Transcriptomic insight into the immune defenses in the ghost moth, Hepialus xiaojinensis, during an Ophiocordyceps sinensis fungal infection. Insect Biochem Mol Biol. 2015; 64:1-15. doi: 10.1016/j.ibmb. 2015.06.014.
  10. Wang, Y.H., Hu, Y., Xing, L.S., Jiang, H., Hu, S.N., Raikhel, A.S. #, Zou, Z#. A Critical Role for CLSP2 in the Modulation of Antifungal Immune Response in Mosquitoes. PLoS Pathog. 2015; 11(6):e1004931. doi: 10.1371/journal.ppat. 1004931.
  11. Xiong, G.H., Xing, L.S., Lin, Z., Saha, T.T., Wang, C., Jiang, H., Zou, Z#. High throughput profiling of the cotton bollworm Helicoverpa armigera immunotranscriptome during the fungal and bacterial infections. BMC Genomics. 2015; 16(1):321. doi: 10.1186/s12864-015-1509-1.
  12. Zou, Z.*, Saha, T.T.*, Roy, S.*, Shin, S.W., Backman, T.W., Girke, T., White, K.P., and Raikhel, A.S. Juvenile hormone and its receptor, methoprene-tolerant, control the dynamics of mosquito gene expression. Proc Natl Acad Sci U S A. 2013; 110(24): E2173-81. doi: 10.1073/pnas.1305293110.
  13. Zou, Z.*, Souza-Neto, J.A.*, Xi, Z., Shin, S.W., Alvarez, K.S., Kokoza, K., Dimopoulos, G., Raikhel, A.S. Transcriptome Analysis of Aedes aegypti Transgenic Mosquitoes with Altered Immunity. PLoS Pathog. 2011; 7(11):e1002394. doi: 10.1371/journal.ppat.1002394.
  14. Zou, Z.*, Shin, S.W.*, Alvarez, K.S., Kokoza, K., Raikhel, A.S. Distinct melanization pathways in the mosquito Aedes aegypti. Immunity. 2010; 32(1):41-53. doi: 10.1016/j.immuni.2009.11.011.
  15. Zou, Z.*, Shin, S.W.*, Alvarez, K.S., Bian, G., Kokoza, K., Raikhel, A.S. Mosquito RUNX4 in the immune regulation of PPO gene expression and its effect on avian malaria parasite infection. Proc Natl Acad Sci U S A. 2008; 105(47):18454-9. doi: 10.1073/pnas.0804658105.
  16. Zou, Z., Evans, J., Lu, Z., Zhao, P., Williams, M., Sumathipala, N., Hetru, C., Hultmark D., Jiang H. (2007) Comparative genomic analysis of the Tribolium immune system. Genome Biol.2007; 8(8):R177. doi:  10.1186/gb-2007-8-8-r177.
  17. Zou, Z., Jiang, H. Manduca sexta serpin-6 regulates immune serine proteinases PAP-3 and HP8. cDNA cloning, protein expression, inhibition kinetics, and function elucidation. J Biol Chem. 2005; 280(14), 14341-8. doi: 10.1074/jbc.M500570200.
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