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    Name:
    		 Lu Hong
    Subject:
    		 Ecological Genomics
    Tel/Fax:
    		 +86-10-64806299  / 
    E-mail:
    		 luhong@ioz.ac.cn
    Address:
    		 The State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
    More:
    		 Genomics of vector insect and virus      

    Resume：

    March 2023 - present: Associate Professor, Institute of Zoology, Chinese Academy of Sciences

    April 2020 - March 2023: Assistant Professor, Institute of Zoology, Chinese Academy of Sciences

    July 2016 - April 2020: Postdoctoral research in Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

    September 2011 - July 2016: Shandong Agricultural University, Tai'an, China. Ph.D. in Agronomy. Major: Agricultural Entomology and Pest Control

    September 2007 - July 2011: Shandong Agricultural University, Tai’an, China. Bachelor in Agronomy. Major: Plant Protection
    Research Interest：

    My main research direction is exploring the molecular mechanisms of the tripartite interactions among vector insects, plant virus and plants. This includes: (1) the function of saliva proteins in the transmission of persistent-propagative plant viruses; (2) the function of saliva proteins in the adaptation of vector insects to their host plants.

    Salivary gland is the key organ for piercing-sucking insects to recognize and accept host plants. Continuous production of watery saliva occurs as piercing-sucking insects probe sieve elements and ingest phloem sap from individual sieve elements. Insect saliva is predicted to contain saliva proteins that modulate plant defenses and facilitate feeding. In recent years, we explore the function of individual protein-effectors in aphid saliva, trying to answer how the genes or proteins in salivary glands regulate the adaptation of aphids to their host plants. At the same time, we also explore the functions of saliva proteins of SBPH in the transmission of RSV.
    Public Services：

    Awards and Honors：

    Research Grants：

    Selected Publication：
    1. Lu H#, Zhu J#, Yu J, Li Q, Luo L, Cui F*. Key role of exportin 6 in exosome-mediated viral transmission from insect vectors to plants. Proc. Natl. Acad. Sci. U.S.A. 2022, 119(36): e2207848119.
    2. Lu H, Li J, Yang P, Jiang F, Liu H, Cui F*. Mutation in the RNA-dependent RNA polymerase of a symbiotic virus is associated with the adaptability of the viral host. Frontiers in Microbiology. 2022, 13: 883436.
    3. Wang W#, Qiao L#, Lu H, Chen X, Wang X, Yu J, Zhu J, Xiao Y, Ma Y, Wu Y, Zhao W, Cui F*. Flotillin 2 facilitates the infection of a plant virus in the gut of insect vector. Journal of Virology. 2022, 96: e0214021.
    4. Tong L#, Chen X#, Wang W#, Xiao Y, Yu J, Lu H, Cui F*. Alternative splicing landscape of small brown planthopper and different response of JNK2 isoforms to rice stripe virus infection. Journal of Virology. 2022, 96: e0171521. Doi: 10.1128/JVI.01715-21.
    5. Ma Y#, Lu H#, Wang W, Zhu J, Zhao W, Cui F*. Membrane association of importin α facilitates viral entry into salivary gland cells of vector insects. Proc. Natl. Acad. Sci. U.S.A. 2021, 118(30): e2103393118.
    6. Zhao W#, Zhu J#, Lu H, Zhu J, Jiang F, Wang W, Luo L, Kang L, Cui F*. The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication. Protein Cell. 2021, 6:1-19.
    7. Lu H, Zhu JJ, Yu JT, Chen XF, Kang L, Cui F. A symbiotic virus facilitates aphid adaptation to host plants by suppressing jasmonic acid responses. Molecular Plant-Microbe Interactions. 2020, 33(1): 55-65.
    8. Chen X, Yu J, Wang W, Lu H, Kang L, Cui F. A plant virus ensures viral stability in the hemolymph of vector insects through suppressing prophenoloxidase activation. mBio. 2020, 11(4): e01453-20.
    9. Li S, Jiang F, Lu H, Kang X, Wang Y, Zou Z, Wen D, Zheng A, Liu C, Liu Q, Kang L, Xia Q*, Cui F*. Mosquito diversity and population genetic structure of six mosquito species from Hainan island. Frontiers in Genetics. 2020, 11:602863.
    10. Cui N#, Lu H#, Wang T, Zhang W, Kang L, Cui F. Armet, an aphid effector protein, induces pathogen resistance in plants by promoting the accumulation of salicylic acid. Philosophical transactions of the Royal Society of London, Series B, Biological sciences. 2019, 374(1767): 20180314.
    11. Zhang LP#, Lu H#, Guo K#, Yao SM, Cui F. Insecticide resistance status and detoxification enzymes of wheat aphids Sitobion avenae and Rhopalosiphum padi. Science China Life Sciences. 2017, 60(8): 927-930.
    12. Lu H#, Yang PC#, Xu YY#, Luo L, Zhu JJ, Cui N, Kang L and Cui F.  Performances of survival, feeding behavior, and gene expression in aphids reveal their different fitness to host alteration. Scientific Reports. 2016, 6: 19344.
    13. Lu H#, Xu YY#, Cui F. Phylogenetic analysis of the ATP-binding cassette transporter family in three mosquito species. Pesticide Biochemistry and Physiology. 2016, 132: 118-124.
    14. Zhu JJ, Jiang F, Wang XH, Yang PC, Bao YY, Zhao W, Wang W, Lu H, Wang QS, Cui N, Li J, Chen XF, Luo L, Yu JT, Kang L and Cui F. Genome sequence of the small brown planthopper, Laodelphax striatellus, GigaScience. 2017, 6(12): 1-12.
    15. Wang W, Luo L, Lu H, Chen SL, Kang L and Cui F. Angiotensin-converting enzymes modulate aphid-plant interactions. Scientific Reports. 2015, 5: 8885.
    16. Guo K, Yang PC, Chen J, Lu H, and Cui F. Transcriptomic responses of three aphid species to chemical insecticide stress. Science China Life Sciences. 2017, 60(8): 931-934.
    17. 陈珍珍, 卢虹, 王跃骅, 曹艳霞, 于金凤, 印象初, 许永玉, 2014. 光周期对中华通草蛉自然越冬成虫及实验种群幼虫耐寒能力的影响. 昆虫学报, 57(1): 52-60.
    18. 许乐园, 米勇, 卢虹, 孙蕾, 陈珍珍, 于金凤, 许永玉, 2014. 麦长管蚜在不同温度下的年龄-龄期生命表. 植物保护学报, 41(6): 673-679.
    19. 于令媛, 时爱菊, 郑方强, 卢虹，张帆, 许永玉, 2012. 大草蛉预蛹耐寒性的季节性变化. 中国农业科学, 45(9): 1723-1730.