Location: Home > Scientists
  Principal Investigators
Name:
 ZHOU Bing
Subject:
 Systems Biology
Tel/Fax:
 +86-10-82619908  / 
E-mail:
 zhoubing@ioz.ac.cn
Address:
 State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences. 1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
More:
 Group of Cell Microenvironment Systems Biology      
Resume:
2018 - present Professor, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
2014 - 2018 Postdoctoral Employee, Department of Cellular and Molecular Medicine, University of California, San Diego; Supervisor: Professor Xiang-Dong Fu
2012 - 2014 Postdoctoral Fellow, Center for Genome Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Supervisor: Professor Xiaofeng Cao
2006 - 2012 Ph.D. in Bioinformatics, Center for Molecular Systems Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences; Supervisor: Professor Jing-Dong Jackie Han
2000 - 2004 B.S. in Information Management & Information Systems, Hunan University

Research Interests:
  1. Development of computational models, tools and pipelines for functional genomics, epigenomics, 4D Nucleome and single cell biology
  2. Development of high-throughput methods and platform for single cell biology
  3. Establishment of models to study cell identity and microenvironment
  4. Systematic research of regulatory mechanisms of cell stemness, plasticity, differentiation and dedifferentiation in the context of multicellular microenvironment

Awards and Honors:

Professional Activities:

Research Grants:

Selected Publications:
  1. Bing Zhou, Xiao Li, Daji Luo, Do-Hwan Lim, Yu Zhou, and Xiang-Dong Fu. GRID-seq for comprehensive analysis of global RNA-chromatin interactions. Nature Protocols, 2019.
  2. Peng Liu^, Shuaibin Zhang^, Bing Zhou^, Xi Luo, Xiaofeng Zhou, Bin Cai, Yinhua Jin, De Niu, Jinxing Lin, Xiaofeng Cao, and Jingbo Jin. The histone H3K4 Demethylase JMJ16 represses leaf senescence in Arabidopsis. The Plant Cell, 2019.
  3. Xiao Li^, Bing Zhou^, Liang Chen, Lan-Tao Gou, Hairi Li, Xiang-Dong Fu. GRID-seq reveals the global RNA-chromatin interactome. Nature biotechnology, 2017.
  4. Jinsong Qiu^, Bing Zhou^, Felicitas Thol, Yu Zhou, Liang Chen, Changwei Shao, Christopher DeBoever, Jiayi Hou, Hairi Li, Anuhar Chaturvedi, Arnold Ganser, Rafael Bejar, Dong-Er Zhang, Xiang-Dong Fu, Michael Heuser. Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators. RNA, 2016.
  5. Xia Cui^, Falong Lu^, Qi Qiu^, Bing Zhou^, Lianfeng Gu, Shuaibin Zhang, Yanyuan Kang, Xiekui Cui, Xuan Ma, Qingqing Yao, Jinbiao Ma, Xiaoyu Zhang, Xiaofeng Cao. REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis. Nature genetics, 2016.
  6. Shuaibin Zhang^, Bing Zhou^, Yanyuan kang, Xia Cui, Ao Liu, Angelique Deleris, Maxim V. C. Greenberg, Xiekui Cui, Qi Qiu, Falong Lu, James A. Wohlschlegel, Steven E. Jacobsen and Xiaofeng Cao. C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association. Cell Discovery, 2015.
  7. Bing Zhou^, Liu Yang^, Shoufeng Li, Jialiang Huang, Haiyang Chen, Lei Hou, Jinbo Wang, Christopher D. Green, Zhen Yan, Xun Huang, Matt Kaeberlein, Li Zhu, Huasheng Xiao, Yong Liu, and Jing-Dong J. Han. Midlife gene expressions identify modulators of aging through dietary interventions. PNAS, 2012.
  8. Hong Yu^, Shanshan Zhu^, Bing Zhou^, Huiling Xue, and Jing-Dong Jackie Han. Inferring causal relationships among different histone modifications and gene expression. Genome Research, 2008.

Patent:

  • Xiang-Dong Fu, Bing Zhou, Xiao Li. Methods for global rna-chromatin interactome discovery. US patent, 2018: US20180039729A1.