姓  名: 顾 奇
学  科: 再生医学
电话/传真: +86-10-64807315 / 
电子邮件: qguATioz.ac.cn
通讯地址: 北京市朝阳区北辰西路1号院5号
中国科学院动物研究所 膜生物学国家重点实验室 100101
更多信息: 生物制造研究组     

简历介绍:

  顾奇,双博士(生物学与材料化学),研究员,现为中国科学院动物研究所生物制造研究组组长。2013年毕业于东北农业大学“国家理科基地班”获得生物学博士学位,2017年毕业于澳大利亚伍伦贡大学获得材料化学博士学位,博士毕业论文被评为优秀毕业论文(Outstanding Thesis),2017年国家优秀留学生。实验室已建立了成熟的3D生物打印平台,主导首次完成了人神经干细胞和人多能性干细胞的3D打印,在三维体系下完成干细胞的原位功能分化,推进了干细胞3D打印领域的进展。目前致力于干细胞相关特异性材料的开发与合成,生物打印平台设计;通过干细胞、生物材料及3D/4D打印的结合进行组织器官的体外再造;深入探讨生物材料、3D微环境及多种物理因素对细胞状态的影响并它们调控细胞/组织的命运。主持和参与多项科研项目,包括中科院A类先导“器官重建与制造”“功能性生物打印‘墨水’及个性化生物3D打印装置研发”方向负责人,战略性国际科技创新合作重点专项负责人。

研究领域:

  生物材料的开发、3D/4D生物打印机的研发与器官的体外重建。

社会任职:

获奖及荣誉:

  • 2017年 伍伦贡大学优秀毕业论文
  • 2017年 国家优秀自费留学生

承担科研项目情况:

  • 2017-2022,中科院A类先导专项“器官重建与制造” “功能性生物打印‘墨水’及个性化生物3D打印装置研发”项目,方向负责人,在研
  • 2019-2023,战略性国际科技创新合作重点专项,首席,在研
  • 2020-2022,中国科学院院级科研仪器设备研制项目,首席,在研

代表论著:

(*共同一作,#共同通信)

  1. Zhao, H., Xu, J., Peng, K., Fu, X., Zhang, E., Lv, F., Liu, L., Zhang, N., Wang, Y., Wang, S., Gu, Q. (2020). Supramolecular Nanofibers for Encapsulation and In Situ Differentiation of Neural Stem Cells. Adv Healthc Mater, e1901295.
  2. Gu, Z., Guo, J., Wang, H., Wen, Y., and Gu, Q. (2020) Bioengineered microenvironment to culture early embryos. Cell Proliferation 53, e12754.
  3. Sun, H., Liu, J., Li, S., Zhou, L., Wang, J., Liu, L., Lv, F., Gu, Q#., Wang, S#. (2019). Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid β Assembly. Angewandte Chemie International Edition 58, 5988-5993.
  4. Gu, Z., Gao, Z., Liu, W., Wen, Y., and Gu, Q. (2019). A Facile Method to Fabricate Anisotropic Extracellular Matrix with 3D Printing Topological Microfibers. Materials 12, 3944.
  5. Wang, L*., Wu, W*., Gu, Q*., Liu, Z., Li, Q., Li, Z., Fang, J., Liu, W., Wu, J., and Zhang, Y. (2019a). The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies. Protein & cell, 1-6.
  6. Sun, H., Lv, F.T., Liu, L.B., Gu, Q.#, Wang, S#. (2018) Conjugated polymer materials for photothermal therapy. Advanced Theraputics 1, 1800057.
  7. Gu, Q., Tomaskovic-Crook, E., Wallace, G.G., and Crook, J.M. (2018) Engineering Human Neural Tissue by 3D Bioprinting, in Biomaterials for Tissue Engineering. Methods in Molecular Biology. 1758: 129-138.
  8. Gu, Q., Tomaskovic-Crook, E., Wallace, G.G., and Crook, J.M. (2017).3D Bioprinting Human Induced Pluripotent Stem Cell Constructs For In Situ Cell Proliferation and Successive Multi-Lineage Differentiation. Advanced Healthcare Materials, doi: 10.1002/adhm.201700175. (cover).
  9. Gu, Q., Tomaskovic-Crook, E., Lozano, R., Chen, Y., Kapsa, R.M., Zhou, Q., Wallace, G.G., and Crook, J.M. (2016). Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells. Advanced Healthcare Materials 5, 1429-1438. (frontispiece)
  10. Chen, Y*., Gu, Q*., Yue, ZL., Crook, Jeremy., Moulton, Simon., Cook, Mark., and Wallace, Gordon. (2017). Development of drug-loaded polymer microcapsules for treatment of epilepsy. Biomaterials Science, 5(10), 2159-2168.
  11. Javadi, M., Gu, Q., Naficy, S., Farajikhah, S., Crook, J., Wallace, G., Moulton, S. (2017) Conductive Tough Hydrogel for Bio-applications. Macromolecular Bioscience. (online)
  12. Zhang, H.R., Gu, Q., Wallace, G.G., Higgins, M.J. (2018). Effect of Electrochemical Oxidation and Reduction on Cell De-Adhesion at the Conducting Polymer-Live Cell Interface as revealed by Single Cell Force Spectroscopy. Biointerphases. 13(4), p.041004.
  13. Gu, Q*., Zhu, H*., Li, J., Li, X., Hao, J., Wallace, G.G., & Zhou, Q. (2016). Three Dimensional Bioprinting Speeds Up Smart Regenerative Medicine. National Science Review 3 (3), 331-344.
  14. Gu, Q*., Hao, J*., Lu, Y., Wang, L., Wallace, G. G., & Zhou, Q. (2015). Three-Dimensional Bio-printing. Science China Life Sciences 58, 411-419. (cover)

写给考生的话:

  Free Your Mind. – Quotes from “The Matrix” (1999)

  博学之,审问之,慎思之,明辨之,笃行之。--《礼记·中庸》