姓 名: |
顾 奇 |
学 科: |
再生医学 |
电话/传真: |
+86-10-64807315 / |
电子邮件: |
qguATioz.ac.cn |
通讯地址: |
北京市朝阳区北辰西路1号院5号 100101 |
更多信息: |
生物制造研究组
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简历介绍:
顾奇,基金委交叉学部优青。现为中国科学院动物研究所研究员,中国科学院器官智造工程实验室主任,北京干细胞与再生医学研究院兼职研究员。2013年毕业于东北农业大学“国家理科基地班”获得生物学博士学位,2017年毕业于澳大利亚伍伦贡大学获得材料化学博士学位。致力于开发干细胞特异生物材料和器官制造平台;结合多技术体系体外再造复杂组织器官系统。首次完成人神经干细胞和人多能性干细胞的3D打印;开发一体化打印技术,实现大尺度血管化组织构建。主持多项科研项目,中科院A类先导“器官重建与制造”中生物墨水和打印装置方向负责人,战略性国际科技创新合作重点专项负责人,院装备项目负责人等。研究成果发表于Adv. Sci., Adv. Funct. Mater., Angew. Chem. Int. Ed., Mater. Horiz., Adv. Healthc. Mater., ACS Appl. Mater. Interfaces等30余篇。
研究领域:
生物材料、生物3D/4D打印、器官制造。
社会任职:
Bioactive Materials (IF=16.8) 青年编委
Cell Proliferation (IF=8.75) 编委
International Journal of Bioprinting (IF=7.42), 客座编辑
获奖及荣誉:
- 2022年 国家自然科学基金委优秀青年基金(交叉学部)
- 2022年 中国干细胞协会卓越青年研究员
- 2017年 国家优秀自费留学生
- 2017年 伍伦贡大学优秀毕业论文
承担科研项目情况:
- 2022-2025, 国家自然科学基金委区域创新发展联合基金,骨干,在研
- 2017-2022,中科院A类先导专项“器官重建与制造” “功能性生物打印‘墨水’及个性化生物3D打印装置研发”项目,方向负责人,在研
- 2019-2023,战略性国际科技创新合作重点专项,首席,在研
- 2020-2022,中国科学院院级科研仪器设备研制项目,首席,在研
代表论著:
(*共同一作,#共同通信)
- Gu, Z.*, Guo, J.*, Zhai, J.*, Feng, G.*, Wang, X., Gao, Z., Li, K., Ji, S., Wang, L., Xu, Y., Chen, X., Wang, Y., Guo, S., Yang, M., Li, L., Han, H., Jiang, L., Wen, Y., Wang, L., Hao, J., Li, W., Wang, S.T.#, Wang, H.M.#, and Gu, Q.# (2022) A Uterus-inspired Niche Drives Blastocyst Development to the Early Organogenesis. Adv. Sci. (frontispiece)
- Liu, X.*, Wang, X.*, Zhang, L.*, Sun, L.*, Wang, H., Zhao, H., Zhang, Z., Liu, W., Huang, Y., Ji, S., Zhang, J., Li, K., Song, B., Li, C., Zhang, H., Li, S., Wang, S.#, Zheng, X.#, Gu, Q.#(2021) 3D Liver Tissue Model with Branched Vascular Networks by Multimaterial Bioprinting. Adv. Healthc. Mater., 2101405. (Cover)
- Fan, T., Wang, S., Jiang, Z., Ji, S., Cao, W., Liu, W., Ji, Y., Li, Y., Shyh-Chang, N. #, Gu, Q. #, (2021). Controllable assembly of skeletal muscle-like bundles through 3D bioprinting. Biofabrication, 14(1), p.015009.
- Gu, Q., Tomaskovic-Crook, E., Lozano, R., Chen, Y., Kapsa, R.M., Zhou, Q., Wallace, G.G.#, and Crook, J.M.# (2016). Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells. Adv. Healthc. Mater. 5, 1429-1438. (frontispiece)
- Gu, Q., Tomaskovic-Crook, E., Wallace, G.G.#, and Crook, J.M.# (2017).3D Bioprinting Human Induced Pluripotent Stem Cell Constructs For In Situ Cell Proliferation and Successive Multi-Lineage Differentiation. Adv. Healthc. Mater., 6(17), p.1700175. (Cover).
- Ding, S.L., Liu, X., Zhao, X.Y., Wang, K.T., Xiong, W., Gao, Z.L., Sun, C.Y., Jia, M.X., Li, C., Gu, Q.#, Zhang, M.Z.#, (2022). Microcarriers in application for cartilage tissue engineering: Recent progress and challenges. Bioact. Mater.
- Zhao, H., Huang, Y., Lv, F., Liu, L., Gu, Q.#, Wang, S.# (2021) Biomimetic 4D-Printed Breathing Hydrogel Actuators by Nanothylakoid and Thermoresponsive Polymer Networks. Adv. Funct. Mater., 2105544.
- Zhao, H., Xu, J., Yuan, H., Zhang, E., Dai, N., Gao, Z., Huang, Y., Lv, F., Liu, L., Gu, Q.# and Wang, S.#, (2021). 3D printing of artificial skin patches with bioactive and optically active polymer materials for anti-infection and augmenting wound repair. Mater. Horiz.
- Zhao, H.*, Xu, J.*, Zhang, E., Qi, R., Huang, Y., Lv, F., Liu, L., Gu, Q.#, Wang, S.# (2021). 3D Bioprinting of Polythiophene Materials for Promoting Stem Cell Proliferation in Nutritionally Deficient Environment. ACS Appl. Mater. Interfaces 13(22): 25759-25770.
- Peng, K., Liu, X., Zhao, H., Lu, H., Lv, F., Liu, L., Huang, Y., Wang, S.# and Gu, Q.# (2021). 3D Bioprinting of Reinforced Vessels by Dual-Cross-linked Biocompatible Hydrogels. ACS Appl. Bio Mater. 4(5), 4549–4556.
- Salahuddin, B., Wang, S., Sangian, D., Aziz, S.#, Gu, Q.# (2021). Hybrid Gelatin Hydrogels in Nanomedicine Applications. ACS Appl. Bio Mater. 4(4), 2886–2906.
- Li, X.*, Wang, Y.*, Ma, R.*, Liu, X., Song, B., Duan, Y., Guo, J., Feng, G., Cui, T., Wang, L., Hao, J.#, Wang, H.M.#, Gu, Q.# (2021). Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro. Biomed. Mater. 16 (3), 035023.
- Zhao, H., Xu, J., Peng, K., Fu, X., Zhang, E., Lv, F., Liu, L., Zhang, N., Wang, Y., Wang, S.#, Gu, Q.# (2020). Supramolecular Nanofibers for Encapsulation and In Situ Differentiation of Neural Stem Cells. Adv Healthc Mater, 9 (1), 1901295.
- Gu, Z., Guo, J., Wang, H., Wen, Y., and Gu, Q. (2020) Bioengineered microenvironment to culture early embryos. Cell Prolif 53, e12754.
- Sun, H., Liu, J., Li, S., Zhou, L., Wang, J., Liu, L., Lv, F., Gu, Q#., Wang, S#. (2019). Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid β Assembly. Angew. Chem. Int. Ed 58, 5988-5993.
- Gu, Z., Gao, Z., Liu, W., Wen, Y., and Gu, Q. (2019). A Facile Method to Fabricate Anisotropic Extracellular Matrix with 3D Printing Topological Microfibers. Materials 12, 3944.
- Gu, Q., Tomaskovic-Crook, E., Wallace, G.G., and Crook, J.M. (2018) Engineering Human Neural Tissue by 3D Bioprinting, in Biomaterials for Tissue Engineering. Methods Mol. Biol. 1758: 129-138.
- Gu, Q.*, Hao, J.*, Lu, Y., Wang, L., Wallace, G. G., & Zhou, Q. (2015). Three-Dimensional Bio-printing. Sci. China Life Sci. 58, 411-419. (cover)
- Gu, Q.*, Zhu, H. , Li, J., Li, X., Hao, J., Wallace, G.G., & Zhou, Q. (2016). Three Dimensional Bioprinting Speeds Up Smart Regenerative Medicine. Natl. Sci. 3 (3), 331-344.
写给考生的话:
Free Your Mind. – Quote from “The Matrix” (1999)
博学之,审问之,慎思之,明辨之,笃行之。--《礼记·中庸》